ロジャー・ラビット

Bob Hoskins

Eddie Valiant

Christopher Lloyd

Judge Doom

Joanna Cassidy

Dolores

Charles Fleischer

Roger Rabbit / Benny the Cab / Greasy / Psycho (voice)

Kathleen Turner

Jessica Rabbit (voice) (uncredited)

Stubby Kaye

Marvin Acme

Alan Tilvern

R.K. Maroon

Richard LeParmentier

Lt. Santino

Lou Hirsch

Baby Herman (voice)

Betsy Brantley

Jessica's Performance Model